随着人们对肽的兴趣持续增长,专家们正越来越多地将目光投向减重之外的领域,探索其在健康衰老方面的潜力。
As interest in peptides continues to grow, experts are increasingly looking beyond weight loss to their potential role in healthy aging.
功能医学专家威尔·科尔(Will Cole)博士在接受福克斯新闻数字频道采访时表示,肽与长寿、细胞修复和代谢健康“息息相关”。
Functional medicine expert Dr. Will Cole told Fox News Digital that peptides are "intimately connected" with longevity, cellular healing and metabolic health.
“(肽)有助于细胞间的通讯,”即将出版的新书《治愈你的细胞》(Heal Your Cells)的合著者科尔说道。他表示,关于肽的使用建议取决于具体的使用背景,并指出答案往往处于“中间地带”。
"[Peptides] help with cellular communication," said Cole, co-author of the upcoming book "Heal Your Cells." The recommendations for peptides depend on the context in which they're used, he said, noting that the answer often falls "somewhere in the middle."
考虑使用肽?医生揭示了随着“狂野西部”式市场扩张,使用肽的关键注意事项。科尔援引此前的研究指出,据估计,93%的美国成年人处于代谢不健康状态,只有约7%的人符合最佳代谢健康的标准——他将这一数字描述为“惊人”。“这很常见,但并不正常,”科尔说。他补充道,虽然GLP-1药物可能有所帮助,但改善代谢健康还需要从生活方式和其他潜在因素入手。
THINKING ABOUT PEPTIDES? DOCTORS REVEAL KEY DOS AND DON’TS AS ‘WILD WEST’ MARKET GROWS Citing previous research, Cole noted that an estimated 93% of U.S. adults are metabolically unhealthy, leaving only about 7% who meet the criteria for optimal metabolic health — a figure he described as "wild." "That's common, but not normal," Cole said. He added that while GLP-1 medications can be beneficial, improving metabolic health also requires addressing lifestyle and other underlying factors.
美国食品药品监督管理局(FDA)将审查7种被吹捧为具有减重、修复和长寿功效的流行肽。科尔表示,他不认为“永远无休止地”大剂量使用GLP-1是改善代谢健康的解决方案。
FDA TO REVIEW 7 POPULAR PEPTIDES TOUTED FOR WEIGHT LOSS, HEALING AND LONGEVITY Cole shared that he does not believe "macro-dosing" GLP-1s "forever and ever in perpetuity" is the solution to improving metabolic health.
虽然GLP-1可以减少对食物的渴望(通常被称为“食物噪音”)并促进减重,但科尔表示,他希望看到更多关于降低食欲是否也会降低对爱、人际关系和其他提升情绪因素的渴望的研究。
While GLP-1s can reduce food cravings — often referred to as "food noise" — and promote weight loss, Cole said he’d like to see more research on how decreasing the desire for food could also decrease cravings for love, relationships and other mood-boosting factors.
科尔质疑,抑制食欲是否会对其他与奖励相关的行为(包括社会关系)产生意想不到的影响。
Cole questioned whether suppressing food cravings could have unintended effects on other reward-related behaviors, including social relationships.
“那么,我们是否在绕过一些本不必被视作‘病理现象’的生理过程呢?”点击此处阅读更多健康相关文章。
"So, are we circumventing pathways and pathologizing things that don't have to be pathologized?" CLICK HERE FOR MORE HEALTH STORIES Cole argued that some degree of hunger signaling is healthy. "Food noise is actually a decent thing in balance, so shutting down your hunger cues with an 'atomic bomb' peptide dose is not the solution."
科尔认为,适度的饥饿信号传递其实对健康是有益的;他说:“在平衡状态下,‘食物相关信号’其实是一种正常的生理现象,因此用高剂量的肽类物质来抑制这些饥饿信号并不是解决问题的正确方法。”他还指出,过度依赖 GLP-1 类药物可能会导致饮食模式紊乱,以及人们对饥饿的恐惧感加剧。
He added that he believes overreliance on GLP-1 medications may contribute to disordered eating patterns and a growing fear of hunger.
科尔将这一现象归因于一种倾向于追求简单、快速解决方案的文化:“人们总是希望有‘灵丹妙药’来解决所有问题。”
Cole attributed the trend to a culture that favors simple, fast solutions over sustained lifestyle changes. "We want a magic pill," he said.
“而事实其实介于两者之间:我们能否通过微量给药来实现治疗效果?能否将这些药物与健康的生活方式相结合呢?”
"And the truth is somewhere in the middle: Can we micro-dose? Can we do it cyclically? And can we pair it with lifestyle?"
专家质疑为何代谢问题会呈“爆发性增长”,并指出其原因包括高摄入超加工食品、营养素缺乏、环境毒素以及压力和创伤等因素。
CLICK HERE TO The expert questioned why there has been an "epidemic rise" of metabolic problems, pointing to factors such as diets high in ultraprocessed foods, nutrient deficiencies, environmental toxins, and the presence of stress and trauma.
“这就是为什么我们会看到慢性健康问题不断增加,而不是因为药物供应不足,”他说。
"That is why we're seeing a rise of chronic health problems, not a pharmaceutical deficiency," he said.
尽管存在这些担忧,科尔仍表示支持扩大肽类药物的普及范围,但他强调透明性、产品纯度以及清晰的产品标签的重要性,这样才能让医疗专业人员和消费者做出明智的选择。点击此处参与我们的最新生活方式问卷测试!
尽管有这些顾虑,科尔仍认为 GLP-1 类药物具有重要的治疗潜力,比如它们有助于减轻炎症、控制自身免疫性疾病并改善肠道健康。
Cole said he supports wider access to peptides, but emphasized the importance of transparency, product purity and clear labeling so healthcare professionals and consumers can make informed decisions. TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ Despite those concerns, Cole said he believes GLP-1s also hold significant therapeutic promise, citing their potential to reduce inflammation, help manage autoimmune conditions and improve gut health.
“不过,关键还是:什么样的最低剂量才能在结合健康生活方式的情况下产生有益效果?我认为这正是肽类药物真正能够发挥作用的地方。”
"But again, what's the lowest dose that yields a beneficial result paired with lifestyle? I think that's where peptides can really shine," he said.
“实际上,我对一些其他类型的肽类(比如具有抗炎作用或延长寿命效果的肽类)更加感兴趣。”
"And I am actually more excited about some of these other [peptides], like the inflammation ones or the longevity peptides."