在接受CNBC-TV18采访时,礼来董事长兼首席执行官戴维·里克斯表示,只要印度监管机构批准该药物,公司就准备立即推出。
Speaking to CNBC-TV18, Eli Lilly Chair and CEO David Ricks stated that the company is ready for an immediate rollout once domestic authorities approve the medication.
美国制药巨头礼来已准备在监管审批完成后,立即将其口服减重及2型糖尿病药物引入印度。印度预计将成为这种药片面向全球供应的生产核心。
US pharmaceutical major Eli Lilly is prepared to introduce its oral obesity and type-2 diabetes drug in India as soon as domestic regulatory clearances come through, with the country set to play a central role in manufacturing the pill for worldwide supply.
“只要印度监管机构批准,我们就准备启动。”里克斯说,并预计该药可能于2027年上市。过去,新分子药物在印度上市通常要等到其全球首次推出后,长则需要四年,而礼来如今正将这一周期压缩至约一年。
"We're ready to go as soon as the Indian authorities say yes," Ricks said, projecting a potential launch in 2027. While introducing new molecules to the Indian market historically took up to four years following their initial global rollout, Lilly is now compressing that window to roughly a single year.
每日一次的小分子药片Foundayo(orforglipron)预计将进入印度市场。这标志着快速演变中的代谢疾病治疗市场正在发生转变,将治疗选择拓展到每周注射型GLP-1药物和双激动剂疗法(如Mounjaro,即替尔泊肽)之外。
The anticipated entry of the oral drug—Foundayo (orforglipron), a once-daily small-molecule pill—marks a shift in the fast-evolving metabolic market beyond weekly injectable GLP-1 and dual-agonist therapies such as Mounjaro (tirzepatide).
在谈及药片相较注射剂的治疗和商业优势时,里克斯表示,尽管口服制剂在峰值效力上可能不及注射剂,但其为患者带来的便利性以及生产规模化“口服药还带来其他几项优势。首先,它用药方便,而且我们确实知道,许多患者不愿尝试注射类药物——他们害怕针头,或者只是因为注射不便于融入日常生活。”里克兹解释道,“第二是可扩展性……对于Foundayo这样的口服药,我们采用化学工艺,可以更快扩大生产。事实上,我们在印度已有多家生产合作伙伴,他们已经在帮助我们向全球供货,我们也已准备好在这里实现超大规模生产。”
Addressing the therapeutic and commercial advantages of a pill over injectables, Ricks noted that while oral formulations may trail behind injectables in sheer peak potency, they offer unmatched consumer convenience and manufacturing scalability.
印度对这家总部位于印第安纳波利斯的药企而言,其重要性远不止患者数量。里克兹确认,礼来正积极落实去年宣布的对印度10亿美元投资承诺,将资金投入合同制造合作和技术能力建设。
"An oral gives us several other advantages. First, it's convenient, and we do know many patients are reluctant to try an injectable medicine—fear of needles, or just doesn't fit into their daily routine," Ricks explained. "The second is scalability... With an oral like Foundayo, we use chemistry, and we can expand that more quickly. In fact, we have several production partners here in India, which are helping us supply the globe already, and we're poised for really massive volume here." India's importance to the Indianapolis-based drugmaker extends well beyond patient volume. Ricks confirmed that Lilly is actively executing its $1 billion investment commitment to India announced last year, directing capital toward contract manufacturing partnerships and technical capabilities.
公司已向印度本土实验室合作伙伴派驻常驻团队,以扩大创新原料药和成品制剂的生产规模。
The company has embedded teams with domestic laboratory partners to scale up production of innovative active pharmaceutical ingredients and finished dosages.
“我们已与印度多家实验室建立合作。而且,这不仅仅是供应商关系。我们会派驻人员与他们一起工作……让他们真正在印度实现规模化生产,并为我们的全球供应链供货。”里克兹表示,礼来正稳步推进计划,未来几年将通过这些合作伙伴落实10亿美元投资。
"We've formed partnerships with several labs in India. And this is not just a supplier relationship. We embed our people with them... and really have them produce at scale here in India and supply our global supply chain," Ricks said, adding that Lilly is well on track to fulfil the $1 billion investment across these partner companies over the next several years.
在开展制造合作的同时,礼来还将其位于海得拉巴的全球技术中心扩充至600多名工程师,专注于人工智能和软件解决方案。
Alongside manufacturing alliances, the group has expanded its global technology centre in Hyderabad to over 600 engineers working on artificial intelligence and software solutions.
礼来于2025年3月携Mounjaro进入印度减重和糖尿病市场,并在推出后的第一年内迅速使其成为当地细分市场领先的品牌疗法。
Lilly entered the Indian weight-loss and diabetes market in March 2025 with Mounjaro, rapidly turning it into the leading branded therapy in the domestic segment within its first year.
在谈及近期大量涌入的低价仿制司美格鲁肽时——其月治疗费用为1,500至5,500印度卢比,而Mounjaro的每月疗程费用为13,000至25,000印度卢比——里克兹表示,仿制药的进入扩大了整体市场,而非削弱了礼来的增长。
Addressing the recent influx of low-cost generic semaglutide versions priced between ₹1,500 and ₹5,500 per month—compared to Mounjaro's ₹13,000 to ₹25,000 monthly regimen—Ricks stated that the arrival of generics has widened the overall market rather than denting Lilly's growth.
单看市场份额可能会产生误导,因为尽管我们的市场份额有所下降,但主要是因为低价仿制药推动市场规模大幅扩张。”里克斯说。“有意思的是,面对这一情况,Mounjaro业务仍实现销量和销售额双增长……我认为,很少有人会[转用其他药物],因为他们对Mounjaro的疗效感到满意。”礼来计划长期将印度打造为其全球前五大市场之一,并扩大临床试验项目和全球“改变进程”(Change the Course)倡议;该倡议聚焦于扩大中低收入国家获得心脏代谢疗法的机会。
"The market share is a little deceiving to look at because although that has fallen for us, it's mostly because the market's expanded so dramatically with lower-price generics," Ricks said. "Interestingly, the Mounjaro business continues to grow in both volume and value through that event... Very few are [switching], I think, because they're satisfied with the performance of Mounjaro." Lilly aims to establish India among its top five global markets over the long term, supported by expanding clinical trial programs and its global "Change the Course" initiative focused on expanding access to cardiometabolic therapies across low- and middle-income countries.