WASHINGTON - While the Iran war smoulders, Saudi Arabia fights the Houthis and a new rift opens in US-Ukraine relations, Secretary of State Marco Rubio travelled on Oct 18 to Uzbekistan, a nation far removed from the biggest US foreign policy challenges.

The top US diplomat landed in Samarkand on the night of Oct 18 to meet with top officials from the C5+1, a grouping that brings together the United States and the Muslim-majority post-Soviet states of Uzbekistan, Kazakhstan, Kyrgyzstan, Tajikistan and Turkmenistan.

US officials have portrayed resource-rich Central Asia – the region between China, Russia and Iran – as worthy of more attention than it received from US President Donald Trump’s predecessors.

Trump hosted C5 leaders at the White House in November 2025, when Kazakhstan agreed to join the Abraham Accords, a series of agreements under which Muslim-majority countries have normalised or deepened relations with Israel.

Separately, Trump met with Uzbek President Shavkat Mirziyoyev at the United Nations General Assembly in September 2025.

Regional politics aside, the trip fits an emerging pattern in which Rubio often visits regions not at the centre of the news cycle, while leaving some more fraught foreign policy portfolios to other Trump aides, including special envoys Steve Witkoff and Jared Kushner and Vice-President J.D. Vance.

Rubio has not visited Kyiv or Moscow since becoming secretary of state and was not present for talks between US and Ukrainian officials in Florida earlier in October, when US officials pressed Ukraine to stop hitting Russian refineries. Vance, not Rubio, represented the US in Pakistan during peace talks with Iran in April. Rubio’s previous foreign trip, in early October, took him to Greece, Portugal and Iceland.

Trump administration officials have typically rejected any suggestion that Cabinet-level officials should focus their travels on geopolitical capitals and hot spots.

Deputy Secretary of State Christopher Landau, for instance, said on X last week that the idea only certain destinations were worthy of visits from secretaries of state “perfectly encapsulates the decadence and degeneracy of the contemporary US foreign policy establishment.”Speaking to reporters before leaving Washington on Oct 17, Rubio said the timing of the Uzbekistan trip was dictated in part by the availability of the various delegations. He also said that foreign trips were too often designed to resolve immediate issues rather than build long-term relationships.

“I mean, one of the things that suffers is the strategic business,” Rubio told reporters. “You’re always visiting someplace where there’s a crisis or there’s a problem or ... you’re going because there’s a conference.”US-Russia relations loom The delegation that greeted Rubio upon his arrival in Samarkand included Uzbek Foreign Minister Bakhtiyor Saidov, whom Rubio embraced warmly. Two women in traditional Uzbek attire presented Rubio and his wife with bouquets.

One Central Asian diplomat, speaking on the condition of anonymity, said officials in the region were wondering to what extent the US would continue targeting Russian sanctions evasion.

All C5 states, while drawing closer to the US, have deep historical ties with Moscow, and the region has facilitated Russian imports and exports that violate US and European Union sanctions, Western officials say. In the past, the US has pushed regional states to clamp down on those illicit flows.

But Trump struck a deal with Moscow in October to import Russian diesel, aimed at lowering domestic fuel prices before congressional midterm elections.

On Oct 16, Trump waived all provisions of legislation that would have allowed him to slap massive tariffs on some nations that buy significant amounts of Russian crude oil or otherwise help Moscow evade sanctions. Among the nations that could have been affected, experts have said, are India and Kazakhstan.

India, which Rubio will visit after Uzbekistan, remains the world’s No. 2 Russian crude importer after China, despite Trump saying in February that India had agreed to stop buying oil from Russia.

Additional questions hang over a potential trade deal with India and an expansion of the Abraham Accords in Central Asia.

A US official, speaking on the condition of anonymity, described the trade deal on Oct 16 as “pretty much done,” raising the possibility that an agreement could be announced during the Rubio trip.

Separately, the US has talked to additional Central Asian nations about joining the Abraham Accords, Reuters reported in 2025 conversations that potentially could continue in Samarkand.

More than 200 business executives are accompanying Rubio to Uzbekistan, the State Department said. The Central Asian diplomat said the Trump administration has focused its commercial efforts on expanding access to the area’s rare earth mineral resources.

After Uzbekistan, Rubio will visit the Indian cities of Mumbai and Jamnagar to meet with business leaders, including Reliance Industries Chairman Mukesh Ambani, who earned the Trump administration’s favour earlier in the year by backing a new refinery in Texas. Rubio most recently visited India five months ago. The trip is due to wrap up on Oct 22.