每个工作日，CNBC投资俱乐部与吉姆·克雷默（Jim Cramer）节目都会发布“收盘前最后一小时”（Homestretch）——一份可操作的下午更新，正好赶上华尔街最后一小时的交易。周一股市普遍上涨，AI交易从上周的大幅亏损中反弹。市场正试图在数据中心主题上重建信心，原因是今天早上出现了三大新闻：Meta Platforms表示计划筹集高达950亿美元的股权融资；SpaceX宣布筹集400亿美元债务融资，用于购买英伟达GPU；Anthropic提交首次公开募股申请。
Every weekday, the CNBC Investing Club with Jim Cramer releases the Homestretch — an actionable afternoon update, just in time for the last hour of trading on Wall Street. Stocks are broadly higher on Monday , with the AI trade rebounding from last week's sharp losses. The market is trying to rebuild confidence in the data center theme following three big news stories this morning: Meta Platforms said it plans to raise up to $95 billion in equity; SpaceX announced a $40 billion debt raise to finance Nvidia GPU purchases, and Anthropic filed for an initial public offering.
随着投资者重新转向AI基础设施股票，他们在上周避险和追求质量行情中表现优异的防御性板块——包括主食消费品、医疗保健和公用事业——上获利了结。本周晚些时候超大规模云服务商的财报将提供关键洞察，了解AI最大投资者的支出计划，以及对AI产品和服务的需求。强生公司股价上涨，此前这家制药巨头公布了1期试验结果，Leerink分析师将其描述为前列腺癌治疗及该公司更广泛肿瘤业务的潜在“颠覆者”。
As investors shifted back into AI infrastructure names, they took profits in defensive sectors such as staples, healthcare, and utilities that had outperformed in last week's flight to safety and quality. Hyperscaler earnings later this week will provide key insights into spending plans among AI's biggest investors, as well as demand for AI products and services. Johnson & Johnson shares moved higher after the pharma giant announced Phase 1 results that Leerink analysts described as a potential "game-changer" for prostate cancer treatment and the company's broader oncology franchise.
强生表示，在接受其实验性每日一次口服药物JNJ-6143治疗的16名患有晚期前列腺癌且肿瘤可测量的患者中，有12人实现了完全或部分肿瘤缓解。这意味着这些患者中有75%对治疗有反应，肿瘤显著缩小或消失。JNJ-6143通过干扰癌细胞功能并诱导癌细胞死亡发挥作用。这些结果意义重大，因为晚期前列腺癌存在巨大的未满足医疗需求。
J & J said 12 of 16 patients with advanced prostate cancer and measurable tumors who received its investigational, once-daily oral drug JNJ-6143 achieved a complete or partial tumor response. This means 75% of those patients responded to treatment, with their tumors shrinking significantly or disappearing. JNJ-6143 works by disrupting cancer cell function and triggering cancer cell death. The results are a big deal because there is a significant unmet need in advanced prostate cancer.
Leerink指出，强生可能会在12月8日的企业业务评审活动上，就该药物的未来开发计划（包括更早的治疗线路）提供新的披露。微软股价小幅上涨，此前该公司宣布向约6万名符合条件的员工提供自愿离职计划。
Leerink noted that J & J could provide new disclosures about the medication's future development plans, including earlier lines of therapy, at its Dec. 8 Enterprise Business Review event. Shares of Microsoft traded slightly higher after the company announced it is offering voluntary buyouts to around 60,000 eligible employees.
与 Netflix 本月初在财报发布前宣布裁员不同，我们不认为微软此次更新预示着其业务放缓。相反，自愿离职买断计划很可能是该公司在投资 AI 基础设施的同时优化运营架构的举措。值得注意的是，微软的支出量入为出，表现优于亚马逊、Alphabet 和 Meta Platforms 等其他主要大规模云服务商。据 FactSet 数据，微软预计即将公布的季度将产生约 80 亿美元的自由现金流，而亚马逊和 Alphabet 分别面临 99 亿美元和 23 亿美元的自由现金流流出。
Unlike Netflix's layoff announcement earlier this month ahead of earnings, we wouldn't view Microsoft's update as a harbinger of a slowdown in its business. Instead, the voluntary buyouts are likely a function of the company optimizing its operating structure as it invests in its AI infrastructure. It's worth mentioning that Microsoft has been spending well within its means — better than the other major hyperscalers like Amazon , Alphabet , and Meta Platforms. Microsoft is expected to generate roughly $8 billion in free cash flow in the soon-to-be-reported quarter, compared with outflows of $9.9 billion at Amazon and $2.3 billion at Alphabet, according to FactSet.
Meta Platforms 上周报告的季度自由现金流流出约为 20 亿美元。这或许能解释为何尽管微软股价在上半年表现疲软，但今年以来仍跑赢了亚马逊、Alphabet 和 Meta。微软将于周三收盘后发布财报，届时我们将更多地了解其营收轨迹和支出计划。Nucor、Celestica、Cadence Design Systems 和 Amkor Technology 将于周一收盘后发布财报。
Meta Platforms reported a quarterly free cash outflow of about $2 billion last week. That could help explain why Microsoft shares have outperformed Amazon, Alphabet and Meta year to date, despite their sluggish performance in the first six months of the year. We'll know more about Microsoft's revenue trajectory and spending plans when it reports earnings on Wednesday after the closing bell. Nucor , Celestica , Cadence Design Systems , and Amkor Technology report after Monday's close.
波音将于周二开盘前发布财报。周二发布财报的其他知名公司包括可口可乐、联合包裹服务、Centene、HCA Healthcare、诺华、自由港-麦克莫兰、Johnson Controls、康宁、PayPal、Sherwin-Williams、Illinois Tool Works 和 Sofi。在数据方面，我们将看到耐用品订单、Conference Board 消费者信心指数和新屋销售数据。()
Before the opening bell on Tuesday, Boeing reports. Other notable companies reporting Tuesday are Coca-Cola , United Parcel Service , Centene , HCA Healthcare , Novartis , Freeport-McMoRan , Johnson Controls , Corning , PayPal , Sherwin-Williams , Illinois Tool Works , Sofi . On the data side, we'll see durable goods orders, Conference Board Consumer Confidence, and new home sales. ()