
Labs总裁马克斯·贾德伯格认为,未来所有药物都将由人工智能研发——唯一的问题是,这个未来到来的速度有多快。
Labs president Max Jaderberg thinks that artificial intelligence will be used to develop all medicines in the future — the only question is how quickly that future will arrive.
贾德伯格周一在伦敦彭博科技大会上表示,该公司利用人工智能加速药物发现、提高效率的努力仍处于临床前试验阶段。同构实验室作为一家公司,正处于其“首局”,他说。
Speaking at the Bloomberg Tech conference in London on Monday, Jaderberg said the company’s efforts to use AI for faster and more efficient drug discovery are still in preclinical trials. Isomorphic is in its “first innings” as a company, he said.
今年1月,同构实验室首席执行官德米斯·哈萨比斯曾表示,该公司预计将在2026年底前进入首次临床试验。
In January, Isomorphic’s Chief Executive Officer Demis Hassabis had said it expected to move into its first clinical trials by the end of 2026.
同构实验室从Alphabet Inc.旗下的Google DeepMind分拆出来,正在为自身的药物研发工作打造人工智能模型,同时也为包括礼来公司和诺华公司在内的生物制药公司提供支持项目。
Spun out of Alphabet Inc.’s Google DeepMind, Isomorphic is creating AI models for its own drug development efforts, as well as to power programs for biopharma companies including Eli Lilly & Co. and Novartis AG.
“这一定会发生。未来所有药物都将由人工智能设计。我对此毫不怀疑。我只是不希望这件事被动地花上20年或50年才发生,”贾德伯格说。
“This will happen. All drugs in the future will be AI-designed. There’s no question in my mind. I just don’t want that to take 20 years or 50 years to happen passively,” Jaderberg said.
这家初创公司迄今已从包括Alphabet和Thrive Capital在内的支持者那里筹集了约27亿美元,彭博社上个月报道称,该公司最近正就新一轮融资进行洽谈,估值可能达到400亿美元或更高。同构实验室在5月最后一次宣布新融资时,未披露其估值。
The startup, which has raised about $2.7 billion to date from backers including Alphabet and Thrive Capital, has recently been in talks for a new funding round that could value it at $40 billion or more, Bloomberg reported last month. Isomorphic didn’t disclose its valuation when it last announced fresh funding in May.
该公司成立于2021年,由时任Google DeepMind首席执行官的哈萨比斯掌舵,旨在基于突破性的蛋白质折叠模型AlphaFold进行开发。8月,哈萨比斯转任DeepMind董事长兼Alphabet首席科学家,但他仍担任同构实验室首席执行官。
The company was founded in 2021 with Hassabis, then Google DeepMind’s CEO, at the helm with plans to build on the breakthrough protein-folding model AlphaFold. In August, Hassabis moved into new roles as DeepMind’s Chair as well as Alphabet’s Chief Scientist, but he remains Isomorphic’s CEO.
同构实验室在自身的药物研发项目中,专注于治疗癌症、免疫系统疾病和炎症的药物。
Isomorphic is focusing on drugs to treat cancer, immune system disorders and inflammation in its own drug development programs.
贾德伯格表示,以往的药物研发在很大程度上是试错过程,结果只能采摘“低垂的果实”。“我认为,作为一个物种,我们其实并不擅长制造药物。我们已经拥有惊人的药物,这本身就是一个奇迹,”他说。
Jaderberg said that previous drug developments were largely trial-and-error and resulted in “low-hanging fruit.”“I believe that we’re not actually very good as a species at creating medicines. It’s a miracle that we have amazing medications already,” he said.
多家 AI 公司正在探索生命科学领域的业务,其中包括 Anthropic PBC,该公司今年早些时候收购了生物技术初创公司 Coefficient Bio,并发布了用于 AI 驱动科学研究的 Claude Science 测试版。其他公司,如获得 OpenAI 支持的 Chai Discovery,正在筹集风险投资,以直接在 AI 药物发现领域与 Isomorphic 竞争。
Numerous AI companies are exploring life science efforts, including Anthropic PBC, which earlier this year bought biotech startup Coefficient Bio and released Claude Science in beta for AI-powered scientific research. Others, like OpenAI-backed Chai Discovery, are raising venture capital to compete with Isomorphic directly on AI drug discovery.