
今年迄今,美国已记录超过5,000例病例。文/玛丽·凯卡托斯 一个会议定于本周举行,将决定美国是否失去其麻疹消除地位。
It comes as the U.S. has recorded more than 5,000 cases so far this year. By Mary Kekatos A meeting is set to take place this week that will determine whether the United States has lost its measles elimination status.
由泛美卫生组织(PAHO)任命的一个由流行病学、公共卫生、病毒学、儿科学和免疫学领域的独立专家组成的小组,将审查证据,以确定美国是否出现了一年的持续传播。
An independent group of experts in epidemiology, public health, virology, pediatrics, and immunization, appointed by the Pan American Health Organization (PAHO), will review evidence to determine whether the U.S. has seen a year of continuous transmission.
美国失去消除地位的威胁迫在眉睫,尤其是在加拿大去年因难以遏制一场持续一年的麻疹疫情而失去其麻疹消除地位之后。
The threat of the U.S. losing its elimination status looms, especially after Canada lost its measles elimination status last year after struggling to contain a year-long measles outbreak.
费城儿童医院疫苗教育中心主任、传染病科主治医师保罗·奥菲特博士对ABC新闻表示:“充其量,失去消除地位将是一声号角。失去这一地位将是巨大的损失。”
"At best, losing the elimination status would be a call to arms," Dr. Paul Offit, director of the Vaccine Education Center and an attending physician in the division of infectious diseases at Children's Hospital of Philadelphia, told ABC News.
美国如何获得麻疹消除地位 根据美国疾控中心(CDC)的数据,在麻疹疫苗问世前的十年里,几乎所有儿童在15岁前都感染过麻疹。
"To lose that status [would be] a tremendous loss." How the U.S. earned measles elimination status In the decade before the measles vaccine became available, nearly all children contracted measles by age 15, according to the CDC.
这家联邦卫生机构估计,美国每年约有300万至400万人患麻疹,约4.8万人住院,约400至500人死亡。约1,000人患脑炎或脑部炎症。
The federal health agency estimates that 3 to 4 million people in the U.S. were sickened by measles every year, about 48,000 were hospitalized and about 400 to 500 people died. About 1,000 people suffered encephalitis or brain inflammation.
1963年,第一种麻疹疫苗问世,1968年又出现了一种改进疫苗。疾控中心数据显示,病例从1963年的385,165例确诊病例下降至1973年的26,686例。
In 1963, the first measles vaccine became available, followed by an improved vaccine in 1968. CDC data show that cases fell from 385,165 confirmed cases in 1963 to 26,686 cases in 1973.

1971年,麻疹、腮腺炎、风疹(MMR)联合疫苗问世,1989年,免疫实践咨询委员会、美国儿科学会和美国家庭医师学会建议儿童接种第二剂MMR疫苗。
In 1971, the measles, mumps, rubella (MMR) combination vaccine became available and, in 1989, the Advisory Committee on Immunization Practices, the American Academy of Pediatrics and the American Academy of Family Physicians recommended that children receive a second MMR dose.
到2000年,年度记录病例已降至仅85例,麻疹在美国被宣布消除,这意味着至少连续12个月没有持续传播。
By 2000, annual recorded cases had fallen to just 85, and measles was declared eliminated in the United States, meaning it was without continuous spread for at least 12 months.
“作为一个国家,我们应该感到自豪,因为我们能够消除世界上最具传染性的传染病,”奥菲特说。“那是一项巨大的成就。”美国麻疹疫情现状2025年1月,得克萨斯州西部一个小镇首次确诊出现麻疹病例。
"We should be proud as a nation that we were able to eliminate the world's most contagious infectious disease," Offit said. "That was an enormous accomplishment." Current state of measles in the U.S. Cases of measles were first confirmed to be cropping up in a small town in western Texas in January 2025.
很快,病毒已蔓延至得克萨斯州邻近各县。其他州也开始报告各自的麻疹疫情,包括犹他州、亚利桑那州、南卡罗来纳州和宾夕法尼亚州。
Soon, the virus had spread to neighboring counties in Texas. Other states began reporting their own measles outbreaks, including Utah, Arizona, South Carolina and Pennsylvania.
在过去近两年里,已确认有11例麻疹死亡病例,主要发生在未接种疫苗的人群或年龄太小无法接种疫苗的人群中。
Over the past nearly two years, 11 measles deaths have been confirmed, largely among unvaccinated individuals or those who were too young to be vaccinated.
目前尚不清楚2025年1月在得克萨斯州确诊的病例是否与其他州的病例有关;如果有关,则意味着美国已出现持续一年的传播。
It's unclear if the cases in Texas that were confirmed in January 2025 are linked to those in other states; if so, it would mean the U.S. has seen a year of continuous transmission.
“如果事实证明所有这些疫情完全独立,无法串联起来,那么你就不能说已经发生了12个月的持续传播,也不能说我们维持了麻疹消除状态,”贝勒医学院国家热带医学院院长、得克萨斯儿童医院疫苗开发中心联合主任彼得·霍特兹博士告诉美国广播公司新闻。
"If it turns out all of those epidemics are entirely separate, and you can't string them together, then you can't say you've had 12 months of continuous transmission and we maintain our measles elimination status," Dr. Peter Hotez, dean of the National School of Tropical Medicine at Baylor College of Medicine and co-director of the Texas Children's Hospital Center for Vaccine Development, told ABC News.
然而,数据可能显示,在所有记录到大规模疫情的州,存在基因完全相同的麻疹病毒。
However, data may show there is genetically identical measles in all states where large outbreaks have been recorded.
“他们可能会查看在这些不同社区传播的毒株是否与[最初在得克萨斯州发现的]毒株相同,或者是否是不同毒株,”奥菲特说。
"They may look at whether or not the strains that are circulating in those different communities are the same strains [first seen in Texas] or whether they're different strains," Offit said.
美国疾病控制与预防中心数据显示,去年全年2025年共报告2,289例确诊病例。在此之前,美国自1992年以来麻疹病例从未超过2,000例。今年已确认至少5,182例麻疹病例,主要分布在45个州和华盛顿特区。
Last year, 2,289 confirmed measles cases were reported for all of 2025, CDC data shows. Prior to this, measles cases had not surpassed 2,000 in the U.S. since 1992. This year, at least 5,182 measles cases have been confirmed, mostly in 45 states and Washington, D.C.
消除状态被取消意味着什么 这一状态是否丧失由泛美卫生组织判定。该组织是联合国下属机构,负责美洲地区的国际卫生事务。
How loss of elimination status works The loss of status is determined by PAHO, an agency of the United Nations that oversees international health in the Americas.
泛美卫生组织设立了一个独立专家机构,名为“麻疹、风疹和先天性风疹综合征消除区域监测与再核实委员会”,该委员会每年至少召开一次会议,监测并再核实该地区各国消除麻疹和风疹的情况。今年的闭门会议将于11月10日至13日举行。
An independent body of experts established by the PAHO -- known as the Measles, Rubella, and Congenital Rubella Syndrome Elimination Regional Monitoring and Re-Verification Commission -- meets at least once a year to monitor and re-verify measles and rubella elimination among countries in the region. This year, the closed-door meeting will take place between Nov. 10 and Nov. 13.

一位了解泛美卫生组织如何判定消除状态丧失的人士今年早些时候告诉ABC新闻,必须要有令人信服的证据,证明自2025年1月以来麻疹在美国持续传播。
A person familiar with how PAHO determines loss of elimination status told ABC News earlier this year that there would have to be compelling evidence that there has been continuous spread of measles in the U.S. since January 2025.
奥菲特和霍特兹表示,判定美国已丧失消除状态——如果这一判定真的作出——不过是个形式而已。
Offit and Hotez said the determination that the U.S. has lost its elimination status -- if it happens -- would merely be a formality.
“麻疹又回来了,”霍特兹说。“你是否把这些特定的疫情联系起来,对我来说,其意义不如我们在美国不同地区已经出现如此广泛的传播这一事实。”
"Measles is back," Hotez said. "Whether or not you connect the dots on these particular epidemics, to me, means less than the fact that we've just got so much widespread transmission in different parts of the U.S."