LEWISTON, MAINE – Former Sen. Joe Manchin, a longtime Democrat turned independent, took aim at Senate Minority Leader Chuck Schumer on Wednesday for trying to unseat Republican Sen. Susan Collins of Maine, calling his former party leader's efforts "crazy" as he joined Collins on the campaign trail in her high-stakes re-election race.

Collins, a moderate Republican who at times has voted against President Donald Trump and her party, is fighting for her political life as she runs for a sixth six-year term representing blue-leaning Maine in the Senate. She is the only GOP senator seeking re-election in a state Trump lost in the 2024 election.

The race between Collins and Troy Jackson, a former state Senate president, is a top flip opportunity for Democrats as they try to win back the Senate majority from Republicans in the midterm elections. The latest public opinion polls indicate a margin-of-error showdown, and the latest Fox News Power Rankings rate the race as a toss-up, as do leading nonpartisan political handicappers the Cook Political Report, Inside Elections and Sabato's Crystal Ball. Manchin, who worked closely with Collins during his years in the Senate, was asked by Fox News Digital how his campaigning with his former colleague would sit with Schumer, the top Democrat in the chamber.

DEMOCRATS THINK A BLUE WAVE IS BUILDING - HERE ARE THREE FACTORS THAT COULD STOP IT "Chuck Schumer would not be surprised of me being with my dear friend.

There is no surprise there at all. I told him he was crazy in 2020 from working against her so hard and he’s crazy now to work against her," Manchin said, as he referred to unsuccessful efforts by Democrats to defeat Collins in her re-election six years ago, and their current push to oust her.

Manchin emphasized, "This is not right. She is the soul of America. She is the soul of the Senate, and he knows he needs more Susan Collins, no matter what side of the aisle they’re on. This is ridiculous." Fox News Digital reached out to Schumer's political team and the Democratic Senatorial Campaign Committee for a comment but did not receive a response at the time this story was published.

A former West Virginia governor who served in the Senate from 2010 to 2025, Manchin frequently broke with his party, frustrating Democratic Presidents Barack Obama and Joe Biden, as well as Schumer and other Senate Democratic leaders.

As he works to oust Collins from the Senate, Jackson has repeatedly tried to anchor the senator to Trump, who has seen his approval ratings in Maine and across the country drop further underwater.

But Manchin said that Collins is "not a Trump senator. She's not a Republican senator or a Democrat senator. She's an American senator that represents her state of Maine ... the most independent minded person I've ever met."

Collins noted that "Joe and I were part of every bipartisan initiative that passed the Senate and became law during the years that we worked together ... I just so enjoy our partnership in getting things done for Maine, for West Virginia and for America." Manchin and Collins spoke with reporters after meeting with restaurant workers and customers at Simones' Hot Dog Stand, a famed local eatery in downtown Lewiston that's been serving customers for a century. It was the first of two campaign stops in Maine's 2nd Congressional District, a key swing district.

Collins and Jackson last week faced off on the debate stage for the fourth and final time. The senator used the debates to showcase how her Senate seniority has helped her deliver federal funding for Maine. Meanwhile, Jackson used the showdowns to position himself as an outsider who understands the struggles and frustrations of working-class voters.

Jackson won a special nominating convention in late July to claim the party's Senate nomination, which was left vacant after primary winner Graham Platner ended his campaign following allegations he raped a woman he previously dated. Platner denied the allegations but dropped out.

Jackson, who earlier this year unsuccessfully ran for the Democratic gubernatorial nomination, had campaigned alongside Platner during the primary campaign.

Collins, meanwhile, has a history of surviving Democratic efforts to unseat her.

Six years ago, she trailed Democratic challenger Sara Gideon, the Maine House speaker at the time, but Collins won re-election by nearly nine points while former President Joe Biden carried the state by a similar margin. Fox News' Kailey Schuyler contributed to this story.